Ayesha began her career by working under Aradhana Seth, on the film Earth 1947. She went on to work with directors including Pankaj Butalia, Mira Nair, Deepa Mehta, Rahul Bose, Daisy Von Mayer, and Farhan Akhtar. In 2005, Ayesha wrote, directed and produced The ‘Cherry On Top’ which received critical acclaim and was screened in competition at film festivals across the world including France, Brazil, Portugal, Spain, Italy, the United States and the United Kingdom.

In 2011 Ayesha co-founded Jamun, an independent film company in Delhi, which has been producing socially engaged content, commissioned commercial work, providing line production services and developing a slate of original fiction and non-fiction content. Ayesha was able to exercise her passions for both visuals and music when directing the second season of The Dewarists , a documentary television series featuring some of the world’s finest musical artists. In 2016, Ayesha lead Jamun in producing India’s first true crime podcast on the Aarushi Talwar case, delving into intense investigative research and non-fiction storytelling.

Since then she has directed and produced multiple documentary series for broadcast and streaming platforms. She has recently directed a 3 part gripping and suspenseful docu-series, 'Indian Predator; The Butcher of Delhi,’ on Netflix and on Amazon Prime Video a series called ‘In Transit’ produced by Tiger Baby. Besides her love for film Ayesha is an obsessive tennis player, loves to play hide and seek with her cats, and enjoys cooking everyday.